Kathleen Sebelius resigned as Health and Human Services Secretary on Friday. Sebelius was the face of Obamacare, the Affordable Care Act. In a Rose Garden ceremony, President Barack Obama nominated his budget director, Sylvia Matthews Burwell from the Office of Management and Budget, as Kathleen Sebelius's successor.

During her tenure, Kathleen Sebelius faced nothing but criticism over the flaw-filled launch of the Obamacare website.

Sebelius took full responsibility for Obamacare's disastrous launch. In October, she told Congress "Hold me accountable for the debacle."

Sebelius continued working until the Affordable Care Act topped a major milestone and met its enrollment goals. Sebelius is former Kansas governor. Prior to that, she was the state's insurance commissioner. Sebelius was sworn in as HHS secretary in April 2009.

According to published reports, President Obama accepted her resignation earlier this week. Sebelius is resigning after five years of service in Obama's cabinet. Kathleen Sebelius is one of the longest serving members of Obama's cabinet.

Obama said he will "miss her advice, I will miss her friendship, I will miss her wit, but I am proud to nominate somebody who holds these ... in abundance, Sylvia Matthews Burwell."

Burwell still has to be confirmed by the Senate as HHS secretary. Her ability to solve Obamacare's problems may depend less on her own competence than on how soon she will be confirmed.

Burwell told CNN's Sanjay Gupta, "There are people in this country who have waited for decades for affordable health coverage for themselves and their families. ... So waiting is not really an option."

Sylvia Matthews Burwell will have to determine how to levy Obamacare's fines and implement the delayed mandate that employers cover their workers.

On April 1, Obama announced that more than 7 million American signed up for private insurance. Republicans says half of Americans disapprove of Obamacare, compared with 37% who are in favor of it, according to a recent Pew poll.

On Thursday, Health and Human Services Secretary Kathleen Sebelius announced "About 7.5 million people have signed up for health insurance through the new state and federal marketplaces. Federal officials have said anyone who tried but was unable to sign up by the deadline will have until April 15 to finish their applications.