Madonna threw shade at Drake after their Coachella 2015 kiss, which inspired a slew of memes over the disgust that showed on the Canadian rapper's face.

In an interactive Q&A for Romeo, one fan asked Madonna about kissing Drake at Coachella 2015.

"You asked the million dollar question. I kissed a girl, and I liked it," she said.

She didn't elaborate, but in another question, she again seemed to have thrown a diss at Drake when she was asked about what to advice her younger self.

"Don't kiss Drake. No matter how many times he begs you to," she said.

According to Daily Mail, Madonna's kiss at Coacheall 2015 wouldn't have been as big of a deal if Drake didn't look disgusted as he wiped his mouth afterwards.

It was captured on camera and shared on all news websites, which inspired a lot of memes. One of the photos likened Madonna to Bram Stoker's "Dracula."

The common theme of the memes was that the kiss was Madonna's secret to looking so young despite her age-by sucking on the energy of the youth, in this case Drake.

But the Canadian rapper insisted that he wasn't grossed out by the Madonna kiss during Coachella 2015.

"Sources close to Drake tell TMZ ... he loved the kiss. As for whether the kiss was prearranged, Drake says it wasn't ... the plan was for Madonna to dance around him while he sat in the chair," the report said.

"Drake says he was not banking on a transfer of the glossy stuff and that's why he blanched," the report added.

Drake also posted on Instagramthe moment Madonna kissed him. The rapper then tried to explain his reaction, "Don't misinterpret my shock!! I got to make out with the queen Madonna and I feel (100) about that forever. Thank you @madonna."